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Durashell

Product Details Ordering Information Download Materials Related video Application Cases

Agela Cleanert SPE cartridge series is centered on a dual-substrate combination, providing high-recovery, highly reproducible sample prep solutions for the pharmaceutical, food, and environmental fields, helping labs work more efficiently.

 

Durashell Hybrid Silicone Filler Series

Wide pH tolerance • High chemical stability • Excellent separation performance

 

Core Features

Extra-wide pH range (1.5–12.0)

  • Using surface ethyl cross-linked hybrid technology, a stable protective layer is formed on the silica gel matrix, making it resistant to strong acid/strong base mobile phases and breaking the usual C18/C8 filler pH limits (2.0–9.0). 
  • You can flexibly optimize separations using pH selectivity, making it suitable for basic compounds, peptides, insulin, and other sensitive substances

 

Excellent chemical stability and long lifespan

  • After 200 hours of extreme pH aging tests (like a pH 12 mobile phase), the column efficiency stayed above 90%, and the retention time remained stable (see the comparison chart).

  • After 12 harsh alkali wash regenerations, key parameters like separation, number of plates, and peak symmetry didn’t change much, greatly cutting down purification costs.

 

High batch reproducibility & mechanical strength

  • High batch reproducibility & mechanical strength
  • Pressure-resistant up to 12 MPa, suitable for various DAC devices to boost flux capacity.

 

Star Products and Use Cases:

Durashell C18

  • Suitable for reverse-phase purification of complex organic compounds, peptides, and traditional Chinese medicine extracts;
  • It can be used for the efficient analysis and preparation of basic drugs like amitriptyline, and under pH 10.5 conditions, the peak symmetry factor can reach 0.63.

Durashell C8

  • Optimized for insulin and peptide samples, it can withstand high pH alkaline cleaning regeneration, addressing the issue of aggregate residues. 
  • Purification peaks of Tresiba insulin and Semaglutide are sharper, and recovery rates are improved.

 

Choose Specification:

  • Filler: 10g/bottle to 5000g/bottle
  • Chromatography column: inner diameter 4.6–50 mm, length 150–250 mm