Welcome to Shanghai HanKing Instrument & Equipment Co.,Ltd

CN/EN

All
  • All
  • Product Management
  • News and Information
  • Enterprise Download

Interchim puriFlash High-Pressure Preparation

Product Details Ordering Information Download Materials Related video Application Cases

 

PuriFlash ® 5.250

Small and Infinite possibilities

 Conventional Flash Purification puriFlash XS 520 Plus Interface Flow rate: 250ml/min   Conventional Flash Purification puriFlash XS 520 Plus Interface Pressure: 250bar


 

Versatility | Flexibility

Suitable for normal-phase or reversed-phase. Flash or Prep Purify.

Powerful features to meet all needs—from routine purification to separation of complex mixtures, impurities, or trace enrichment.

Organic small molecule

●●●●●

Impurity Identification

●●●●●

Natural product

●●●●●

Polypeptide, oligonucleotide

●●●○○

Proteins, biopharmaceuticals

●●○○○

Separation of metabolites

●●●●●

Trace analysis

●●●●●

 

 

 

 


 


 


 


 


 

Intersoft ® X Genius Smart software

User-friendly interface, easy to operate, and intelligent method development.

Control module

15 Inch touchscreen

Remote control

USB x 8 RJ45

Fraction collector

3 a reagent rack

132 pipe 18 x 150 mm

Leakage and Waste Disposal System

Chromatographic column

Inner diameter can reach 80 mm

Injection system

Supports liquid sample injection and dry sample loading.

Column balance

Load & Go Technology

Six-way valve +10 Valve-controlled solid-phase loading

UV 200-400nm

UV 200-800nm

(Pack-UV extended)

Multi-wavelength and full-spectrum scanning for spectral visualization and purity confirmation.

Flow cell: 0.3 mm / 40 µL

Optional Pack-iELSD

 

 

 

 

PuriFlash ® 5.400 UV

Step into Ultrapure

 Conventional Flash Purification puriFlash XS 520 Plus Interface Flow rate: 125ml/min   Conventional Flash Purification puriFlash XS 520 Plus Interface Pressure: 400bar

 

Method development and purification of rare, high-value compounds

From method development for small-diameter chromatographic columns to preparative-scale applications—all on the same instrument. HPLC Purification—this system offers greater flexibility, saves time, and boosts productivity; with 2 mu m Compatible with chromatographic columns to achieve greater separation capability.

Organic small molecule

●●●●●

Impurity Identification

●●●●●

Natural product

●●●●●

Polypeptide, oligonucleotide

●●●●○

Proteins, biopharmaceuticals

●●○○○

Separation of metabolites

●●●●●

Trace analysis

●●●●●

 

 

 


 


 


 


 


 

Intersoft ® X Genius Smart software

User-friendly interface, easy to operate, and intelligent method development.

Control module

15 Inch touchscreen

Remote control

USB x 8 RJ45

Fraction collector

3 a reagent rack

132 pipe 18 x 150 mm

Leakage and Waste Disposal System

Chromatographic column

Inner diameter can reach 660 mm

Injection system

Supports liquid sample injection and dry sample loading.

Column balance

Load & Go Technology

Six-way valve +10 Valve-controlled solid-phase loading

UV 200-400nm

UV 200-800nm

(Pack- UV extended)

Multi-wavelength and full-spectrum scanning for spectral visualization and purity confirmation.

Flow cell: 1.0 mm / 20 µL

 

| Ultraviolet - Visible Spectrophotometer Detector

 

Choose the UV that suits your needs. - Visible Spectrophotometer Detector

PuriFlash Ultraviolet included with the device - The visible spectrophotometer detector is fully integrated into the acquisition module, and is composed of... InterSoft X Software control. Since the application is very simple, you only need to enter the desired wavelength into the software and can simultaneously select... 4 a single wavelength, in a manner identical to scanning (the total number of wavelengths available for both models can be included in this model), “Genius” Will be responsible for the acquisition and recording of chromatograms.

Each laboratory has different needs, and since we are eager to meet these needs and always provide you with the right solution, we recommend using two types of UV detectors:

200 – 400 nm (Standard For proteins PF-020B Except)

200 – 800 nm (Compatible with this option) PuriFlash ® of the UV Expansion pack)

 

Real-time scanning across the entire wavelength and ultraviolet spectrum

Ultraviolet - The visible spectrophotometer detector is equipped with... “DAD” Technology (diode-array detector). This provides approximately one hundred diodes for scanning the entire wavelength range for detection, enabling real-time acquisition of the UV spectra of eluting compounds.

If you wish, you can at any time—even during operation or reprocessing—return to the peaks in the chromatogram to display the spectrum at the selected time and obtain identification of the elements as well as the purity of the purified compound.

| Integration ELSD Evaporative Light Scattering Detector

 

Ø   ELSD For General detector It can be used very flexibly in either normal-phase or reversed-phase mode, and also supports isocratic separation or multi-solvent gradient methods. ELSD The response factor is always constant.

Ø   Compared to a UV detector, ELSD Can detect all compounds. including carbohydrates, peptides, amino acids, fats, polymers, and sugars (polysaccharides, oligosaccharides), PEG And protein.

Ø   ELSD With experts in this field To sit Close collaboration aimed at meeting rapid and purification requirements and eliminating common limitations. ELSD Equipped with a fully functional atomizer to eliminate any risk of clogging.

Ø   PuriFlash Integrated with ELSD When combined, this method can purify raw materials ranging from a few milligrams to several hundred grams. In routine operations, the elution flow rate (up to 200mL/min ) and use F0001 To F0800 of the PuriFlash Chromatographic column for high performance.

Ø   Low-temperature technology Higher sensitivity is achieved through a unique atomizer and a highly efficient photomultiplier tube.

With this proprietary technology, droplets dry more quickly at low temperatures, providing adequate signal intensity for semivolatile compounds. This technology does not require additional equipment, such as sprayers (spray chambers) with heating systems or evaporation tubes. Peltier Cooling).

Ø   Dynamic gain SAGA by Interchim and To sit Co-created, with automatic gain adjustment, enabling... ELSD Without saturation, sensitivity remains unaffected. Detector: High-sensitivity photodiode

Source LED ( 470nm )

Ambient temperature: up to 100 Celsius

Dynamic: 40 mu L/min sample in DEDL

Gas: 1–1.5 L/min – 1 bar

Ø   Through InterSoft X The software performs control.

If not used during the purification process ELSD Then, costs can be saved by turning off the lights and gas.

At the end of each purification, ELSD The dynamic separator automatically cleans itself to ensure proper operation.

 

 

Configuration

PuriFlash ® 5.250

PuriFlash ® 5.400UV

Pump

Flow rate (ml/min)

250

125

Maximum pressure (bar)

250

400

Quadruple Gradient Pump

Air venting

X

Washing discs

Pump Washing Discs (Pack)

Pack-PWD

Pack-PWD

Detector

UV: 200 – 400 nm

UV: 200 – 800 nm

Pack-UVextended

Pack-UVextended

Purity Confirmation

iELSD (pack)

pack-iELSD

pack-iELSD

pH/ Electrical conductivity

X

X

Load sample

4 Electrically operated valve

X

X

6 Electrically operated valve w/loop

X

X

6 Pass-through valve +10 Electrically operated valve w/loop

(1/16” & 0.75mm) )

Liquid, Dry-Load Load sample

X

Chromatographic Column Selection Valve

14port/6 Electrically operated valve

X

X

6 Electrically operated valve

Pack-Multi

X

System Configuration

Tubings – after pump (ID)

1/8” x 1.6mm

55~1/16” x 0.5mm

Flow cell

0.3mm/40 mu L

1.0mm/20 mu L

Chromatography column holder

Integration

Pre-column Column support

X

Fraction collection

Regular

3 a reagent rack

132 pipe 18x150mm

3 a reagent rack

132 pipe 18x150 mm

Control module

15 Inch touchscreen

USB

8

8

RJ45

Software

Intersoft X

Safety

Leak detection (pump, collection rack, iELSD , bracket)

X

Solvent tray with drainage system

Collector with drainage system

Solvent level monitoring

RFID

Fume Enclosure

Size

E:D:H (cm)

40×51×75

40×51×75

Introduction to AIS Purification and Preparation Systems and Organic Mass Spectrometry Products

5.2MB

文件下载
< 1 >