The 6th Annual Bio-Process Industry Summit—Hanyao invites you to booth 07!

The 6th Annual Bio-Industry Summit 2024 (BioONE2024) Co-organized by East China University of Science and Technology and BioValley, it will be held on... November 12, 2024 In Shanghai The conference will be held. Over the past few decades, biomanufacturing technologies have undergone tremendous transformations. While early biomanufacturing relied on traditional unit operations, modern biomanufacturing leverages cutting-edge technologies such as synthetic biology and gene editing—precisely manipulating DNA to achieve predictable and quantifiable biological traits, thereby enabling highly efficient products and processes. These technological advances are meeting an ever-growing range of complex biomanufacturing needs. Meanwhile, continuous optimization of bioprocesses is not only driving the development of pharmaceuticals but also playing a crucial role in the diversified growth of medical aesthetics and other bioactive ingredient-based products. As always, this conference will invite CMC and production experts, scholars, and university professors from across the industry, providing industry peers with a rich platform for mutual exchange in the field of bioprocessing. Shanghai Hanyao will showcase its 908devices products at the event. Booth 07 We look forward to your visit.

Exhibit Introduction

908 Devices Upstream Process Development Support Tool

908 Devices, a pioneer in microfluidic chips for chemical and biomolecular analysis, acquired Trace, a German specialist in enzyme-membrane sensors, in 2022, thereby expanding its product lineup. The new product enables real-time, online monitoring of glucose and lactate concentrations in bioreactors and supports feedback-based feeding adjustments—without any loss of sample volume throughout the entire process.

Online Biochemical Analyzer MAVEN

Optimized, automated, and worry-free glucose and lactate monitoring.

Monitoring and controlling glucose and lactate concentrations during cell culture and fermentation is crucial for achieving optimal process efficiency and productivity, thereby facilitating the seamless implementation of PAT strategies. Real-time insights into the metabolic state of cells are of great significance for optimizing the culture medium and developing feeding and control strategies.

Maverick Raman Spectroscopy PAT System

A plug-and-play multi-parameter PAT tool that enables online monitoring in just a few minutes.

Based on Raman spectroscopy principles and three built-in models, this system can simultaneously and in real time measure three key process parameters—glucose, lactate, and total cell density (TCD)—in a validated full range of CHO and HEK293 cell cultures. It can also connect up to six reactors simultaneously, helping to overcome the high upfront costs associated with traditional Raman-based methods. Compared to conventional Raman PAT instruments, this system offers plug-and-play functionality for real-time monitoring of the three core parameters as well as OPC-UA feedback control. Moreover, it complies with 3Q and 21 CFR Part 11 requirements, enabling rapid automation—from process development through pilot-scale amplification production.

REBEL

Instructions for Use and Sample Handling:

What you see is what you get.

The REBEL side does not require an external computer, compressed gas cylinder, waste container, or reagent bottle.

All you need to do is centrifuge or filter the sample (1) to remove cells, then dilute it with REBEL diluent (2). Next, load the sample into the device (3) and press “start” (4). All calibration standards and reagents are stored inside the REBEL instrument, and the data will be automatically processed into a report (in CSV or PDF format), which can be exported via USB flash drive (5).

Keywords:

Sterile Thin-Film Evaporator

A Highlight Reel of the Biopharmaceutical and Formulation R&D Innovation Conference