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2025

Revolutionizing Peptide Synthesis: PurePep Sonata+ Achieves Efficiency in Just Six Steps

Meet stringent production capacity requirements with real-time traffic technology and intuitive software.

Real-time traffic technology —— Achieves accurate and precise fluid transfer with virtually no need for calibration.

Pre-programmed standard method —— It can be used directly or as a template for custom methods.

Import sequence —— Easily create synthesis processes using the key library.

Multitasking —— While one synthesis process is running, another synthesis process plan is being developed.

Automatic calculation —— Use the reagent preparation, cost, and dosage calculator built into the software.

Adjustable blending mode —— Nitrogen bubbling, stirring, and recirculation are employed to enhance purity.

Peptide synthesis : Simple 6 Footwork

The first 1 Step :

Input parameters, including the coupling method, reagent excess, and resin information, are used for record keeping and calculation.

The first 2 Step :

Add a peptide from the library, or create a new peptide using the sequence editor. Select the one corresponding to Single-Sho. ^TM The loop of the addition process.

The first 3 Step :

Choose whether to use the default positions for amino acids and reagents, or rearrange them as needed.

The first 4 Step :

Assign pre-programmed or custom chemical protocols to all cycles in the synthesis. If high-purity coupling is used, adopt the custom mixing mode.

The first 5 Step :

Wait for the software to calculate all the required reagent weights and volumes, as well as the theoretical yield, estimated synthesis time, and cost.

The first 6 Step :

Synthesis can be started from scratch or from any desired cycle and step. Check the current cycle’s status and follow the countdown to complete peptide synthesis.

Real-time traffic technology

Using real-time traffic technology To meet stringent production capacity requirements.

Precise and accurate fluid transfer: Use sonar technology to continuously monitor the flow rate of fluids with varying viscosities.

Reduce calibration requirements: All fluid transfers require only one calibration.

Rapid fluid transfer: No need to measure the solvent—real-time flow technology helps you complete fluid transfer quickly and accurately.

21 CFR Part 11 Compliance and IQ/OQ/PQ

PurePep ^® The software was designed with compliance in mind according to 21 CFR Part 11, ensuring that the instrument can be used in highly regulated CGMP laboratory environments. We can also provide IQ/OQ support and PQ guidance.

The main software features include:

User Management
Electronic signature
Audit trail
Easy-to-view reports enhance traceability.

Multiple hybrid modes

No matter the amount of resin used, our three mixing modes can ensure you achieve the ideal mixing result. The mixing modes can be executed individually or combined as needed.

Nitrogen bubbling

- Nitrogen flow rate is adjustable.

Stir

- The vortex speed is adjustable.

Recycling

- Reagent recycling via the reaction vessel

Purity: PurePep Pathway-specific chemically inert flow path

Productivity: Real-time flow control for accurate and precise fluid delivery.

Efficacy: Achieving pilot-scale synthesis of high-purity peptides

Keywords:

Symphony®X Multichannel Peptide Synthesizer

The 11th National Peptide Drug Exchange Conference.