A Highlight Reel of the 6th BioONE2024 Annual Summit for the Bioprocessing Industry

November 12 ， BioONE2024 6th Annual Bio-Process Industry Summit Grandly inaugurated at the Shanghai Baohua Marriott Hotel! This conference is guided by the Chinese Society for Microbiology and the Shanghai Biomedical Technology Industry Promotion Center, organized by East China University of Science and Technology and BioValley, and supported by the “Innovation China” Biomedical Industry Technology Service Team.

As a professional provider of products and technical services, Shanghai Hanyao Instrument & Equipment Co., Ltd. has consistently focused on delivering high-quality products and technical services to users in China’s biopharmaceutical, food, and chemical laboratory industries. At this exhibition, we are showcasing our 908devices products to introduce and demonstrate their unique advantages to professionals from various sectors of the industry.

Exhibit Introduction

908 Devices Upstream Process Development Support Tool

908 Devices, a pioneer in microfluidic chips for chemical and biomolecular analysis, acquired Trace, a German specialist in enzyme membrane sensors, in 2022, thereby expanding its product lineup. The new product enables real-time, online monitoring of glucose and lactate concentrations in bioreactors and supports feedback-based feeding adjustments—without any loss of sample volume throughout the entire process.

Online Biochemical Analyzer MAVEN

Optimized, automated, and worry-free glucose and lactate monitoring.

Monitoring and controlling glucose and lactate concentrations during cell culture and fermentation is crucial for achieving optimal process efficiency and productivity, thereby facilitating the seamless implementation of PAT strategies. Real-time insights into the metabolic state of cells are essential for optimizing the culture medium and developing feeding and control strategies.

Maverick Raman Spectroscopy PAT System

A plug-and-play multi-parameter PAT tool that enables online monitoring in just a few minutes.

Based on Raman spectroscopy principles and three built-in models, this system can simultaneously and in real time measure three key process parameters—glucose, lactate, and total cell density (TCD)—in a validated full range of CHO and HEK293 cell cultures. It can also connect up to six reactors simultaneously, helping to overcome the high upfront costs associated with traditional Raman-based methods. Compared to conventional Raman PAT instruments, this system offers plug-and-play functionality for real-time monitoring of the three core parameters as well as OPC-UA feedback control. Moreover, it complies with 3Q and 21 CFR Part 11 standards, enabling rapid automation—from process development through pilot-scale amplification production.

REBEL

Usage and Sample Handling:

What you see is what you get.

The REBEL side does not require an external computer, compressed gas cylinders, waste containers, or reagent bottles.

All you need to do is centrifuge or filter the sample (1) to remove cells, then dilute it with REBEL diluent (2). Next, load the sample into the device (3) and press “start” (4). All calibration standards and reagents are stored inside the REBEL instrument, and the data will be automatically processed into a report (in CSV or PDF format), which can be exported via USB flash drive (5).

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Review of the 10th Conference on Cutting-Edge Technologies for Peptide Drug R&D and Scale-Up Production

Booth 3230, Hall N3, Shanghai New International Expo Center, November 18