Highlights from the 2024 BIOCHINA South China Conference

2024 BIOCHINA South China Yu October 10-11, 2024 In Guangzhou The meeting was held, and Shanghai Hanyao Instrument & Equipment Co., Ltd. (hereinafter referred to as “Hanyao”), as a provider of products and technical services, brought along... 908 Devices Brand products unveiled. S073 Booths will jointly explore the current status and development trends of the South China bioindustry.

Exhibit Introduction

908 Devices Upstream Process Development Support Tool

908 Devices, a pioneer in microfluidic chips for chemical and biomolecular analysis, acquired Trace, a German specialist in enzyme membrane sensors, in 2022, thereby expanding its product lineup. The new product enables real-time, online monitoring of glucose and lactate concentrations in bioreactors and supports feedback-based feeding adjustments—without any loss of sample volume throughout the entire process.

Online Biochemical Analyzer MAVEN

Optimized, automated, and worry-free glucose and lactate monitoring.

Monitoring and controlling glucose and lactate concentrations during cell culture and fermentation is crucial for achieving optimal process efficiency and productivity, thereby facilitating the seamless implementation of PAT strategies. Real-time insights into the metabolic status of cells are essential for optimizing the culture medium and developing feeding and control strategies.

Maverick Raman Spectroscopy PAT System

A plug-and-play multi-parameter PAT tool that enables online monitoring in just a few minutes.

Based on Raman spectroscopy principles and three built-in models, this system can simultaneously and in real time measure three key process parameters—glucose, lactate, and total cell density (TCD)—in a validated full range of CHO and HEK293 cell cultures. It can also connect up to six reactors simultaneously, helping to overcome the high upfront costs associated with traditional Raman-based methods. Compared to conventional Raman PAT instruments, this system offers plug-and-play functionality for real-time monitoring of the three core parameters as well as OPC-UA feedback control. Moreover, it complies with 3Q and 21 CFR Part 11 standards, enabling rapid automation—from process development through pilot-scale amplification production.

REBEL

Instructions for Use and Sample Handling:

What you see is what you get.

The REBEL side does not require an external computer, compressed gas cylinder, waste container, or reagent bottle.

All you need to do is centrifuge or filter the sample (1) to remove cells, then dilute it with REBEL diluent (2). Next, load the sample into the device (3) and press “start” (4). All calibration standards and reagents are stored inside the REBEL instrument, and the data will be automatically processed into a report (in CSV or PDF format), which can be exported via USB flash drive (5).

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A Highlight Reel of the Biopharmaceutical and Formulation R&D Innovation Conference

The Biopharmaceutical and Formulation R&D Innovation Conference—Hanyao looks forward to your attendance!